To just run NO, but if you want to see anything more than 15 lbs of boost you will need a DLI or CDI box. I could only get around 15-16 lbs before it would misfire then I added the DLI and no more misfire.
You definatley need an ignition. Seriously, If you've come this far as to go single/big twin, and an aem ems, just buck up and get a dli. I can't see spending all that money and ruin something over spark. good luck with the build!